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Design of a nanostructured lipid carrier intended to improve the treatment of tuberculosis

This work aimed to design, develop, and characterize a lipid nanocarrier system for the selective delivery of rifabutin (RFB) to alveolar macrophages. Lipid nanoparticles, specifically nanostructured lipid carriers (NLC), were synthetized by the high-shear homogenization and ultrasonication techniqu...

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Detalles Bibliográficos
Autores principales: Pinheiro, Marina, Ribeiro, Ricardo, Vieira, Alexandre, Andrade, Fernanda, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977088/
https://www.ncbi.nlm.nih.gov/pubmed/27536067
http://dx.doi.org/10.2147/DDDT.S104395