Endoplasmic reticulum stress-induced autophagy determines the susceptibility of melanoma cells to dabrafenib

Melanoma is one of the deadliest skin cancers and accounts for most skin-related deaths due to strong resistance to chemotherapy drugs. In the present study, we investigated the mechanisms of dabrafenib-induced drug resistance in human melanoma cell lines A375 and MEL624. Our studies support that bo...

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Detalles Bibliográficos
Autores principales: Ji, Chao, Zhang, Ziping, Chen, Lihong, Zhou, Kunli, Li, Dongjun, Wang, Ping, Huang, Shuying, Gong, Ting, Cheng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977101/
https://www.ncbi.nlm.nih.gov/pubmed/27536070
http://dx.doi.org/10.2147/DDDT.S112740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977101/
https://www.ncbi.nlm.nih.gov/pubmed/27536070
http://dx.doi.org/10.2147/DDDT.S112740

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