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Endoplasmic reticulum stress-induced autophagy determines the susceptibility of melanoma cells to dabrafenib
Melanoma is one of the deadliest skin cancers and accounts for most skin-related deaths due to strong resistance to chemotherapy drugs. In the present study, we investigated the mechanisms of dabrafenib-induced drug resistance in human melanoma cell lines A375 and MEL624. Our studies support that bo...
Autores principales: | Ji, Chao, Zhang, Ziping, Chen, Lihong, Zhou, Kunli, Li, Dongjun, Wang, Ping, Huang, Shuying, Gong, Ting, Cheng, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977101/ https://www.ncbi.nlm.nih.gov/pubmed/27536070 http://dx.doi.org/10.2147/DDDT.S112740 |
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