Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches

Rosmarinic acid (RA) possesses several protective bioactivities that have attracted increasing interest by nutraceutical/pharmaceutical industries. Considering the reduced bioavailability after oral use, effective (and safe) delivery systems are crucial to protect RA from gastrointestinal degradatio...

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Detalles Bibliográficos
Autores principales: Madureira, Ana Raquel, Nunes, Sara, Campos, Débora A, Fernandes, João C, Marques, Cláudia, Zuzarte, Monica, Gullón, Beatriz, Rodríguez-Alcalá, Luís M, Calhau, Conceição, Sarmento, Bruno, Gomes, Ana Maria, Pintado, Maria Manuela, Reis, Flávio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977102/
https://www.ncbi.nlm.nih.gov/pubmed/27536103
http://dx.doi.org/10.2147/IJN.S104623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977102/
https://www.ncbi.nlm.nih.gov/pubmed/27536103
http://dx.doi.org/10.2147/IJN.S104623

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