Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in regulating synapse numbers, thus unravelling...

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Detalles Bibliográficos
Autores principales: Voelzmann, Andre, Okenve-Ramos, Pilar, Qu, Yue, Chojnowska-Monga, Monika, del Caño-Espinel, Manuela, Prokop, Andreas, Sanchez-Soriano, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977155/
https://www.ncbi.nlm.nih.gov/pubmed/27501441
http://dx.doi.org/10.7554/eLife.14694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977155/
https://www.ncbi.nlm.nih.gov/pubmed/27501441
http://dx.doi.org/10.7554/eLife.14694

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