Ring-like oligomers of Synaptotagmins and related C2 domain proteins

We recently reported that the C2AB portion of Synaptotagmin 1 (Syt1) could self-assemble into Ca(2+)-sensitive ring-like oligomers on membranes, which could potentially regulate neurotransmitter release. Here we report that analogous ring-like oligomers assemble from the C2AB domains of other Syt is...

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Detalles Bibliográficos
Autores principales: Zanetti, Maria N, Bello, Oscar D, Wang, Jing, Coleman, Jeff, Cai, Yiying, Sindelar, Charles V, Rothman, James E, Krishnakumar, Shyam S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977156/
https://www.ncbi.nlm.nih.gov/pubmed/27434670
http://dx.doi.org/10.7554/eLife.17262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977156/
https://www.ncbi.nlm.nih.gov/pubmed/27434670
http://dx.doi.org/10.7554/eLife.17262

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