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Identification of a role for the nuclear receptor EAR-2 in the maintenance of clonogenic status within the leukemia cell hierarchy

Identification of genes that regulate clonogenicity of acute myelogenous leukemia (AML) cells is hindered by the difficulty of isolating pure populations of cells with defined proliferative abilities. By analyzing the growth of clonal siblings in low passage cultures of the cell line OCI/AML4 we res...

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Detalles Bibliográficos
Autores principales: Ichim, CV, Atkins, HL, Iscove, NN, Wells, RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977185/
https://www.ncbi.nlm.nih.gov/pubmed/21637284
http://dx.doi.org/10.1038/leu.2011.137