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DNA Damage Response and Immune Defense: Links and Mechanisms

DNA damage plays a causal role in numerous human pathologies including cancer, premature aging, and chronic inflammatory conditions. In response to genotoxic insults, the DNA damage response (DDR) orchestrates DNA damage checkpoint activation and facilitates the removal of DNA lesions. The DDR can a...

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Detalles Bibliográficos
Autores principales: Nakad, Rania, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977279/
https://www.ncbi.nlm.nih.gov/pubmed/27555866
http://dx.doi.org/10.3389/fgene.2016.00147