Actin and DNA Protect Histones from Degradation by Bacterial Proteases but Inhibit Their Antimicrobial Activity

Histones are small polycationic proteins located in the cell nucleus. Together, DNA and histones are integral constituents of the nucleosomes. Upon apoptosis, necrosis, and infection – induced cell death, histones are released from the cell. The extracellular histones have strong antimicrobial activ...

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Detalles Bibliográficos
Autores principales: Sol, Asaf, Skvirsky, Yaniv, Blotnick, Edna, Bachrach, Gilad, Muhlrad, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977296/
https://www.ncbi.nlm.nih.gov/pubmed/27555840
http://dx.doi.org/10.3389/fmicb.2016.01248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977296/
https://www.ncbi.nlm.nih.gov/pubmed/27555840
http://dx.doi.org/10.3389/fmicb.2016.01248

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