Microglial Priming and Alzheimer’s Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?

Neuroinflammation is thought to contribute to Alzheimer’s disease (AD) pathogenesis that is, to a large extent, mediated by microglia. Given the tight interaction between the immune system and the brain, peripheral immune challenges can profoundly affect brain function. Indeed, both preclinical and...

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Detalles Bibliográficos
Autores principales: Hoeijmakers, Lianne, Heinen, Yvonne, van Dam, Anne-Marie, Lucassen, Paul J., Korosi, Aniko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977314/
https://www.ncbi.nlm.nih.gov/pubmed/27555812
http://dx.doi.org/10.3389/fnhum.2016.00398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977314/
https://www.ncbi.nlm.nih.gov/pubmed/27555812
http://dx.doi.org/10.3389/fnhum.2016.00398

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