C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors

C3 exoenzyme from C. botulinum is an ADP-ribosyltransferase that inactivates selectively RhoA, B, and C by coupling an ADP-ribose moiety. Rho-GTPases are involved in various cellular processes, such as regulation of actin cytoskeleton, cell proliferation, and apoptosis. Previous studies of our group...

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Detalles Bibliográficos
Autores principales: von Elsner, Leonie, Hagemann, Sandra, Just, Ingo, Rohrbeck, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977334/
https://www.ncbi.nlm.nih.gov/pubmed/27351882
http://dx.doi.org/10.1007/s00210-016-1270-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977334/
https://www.ncbi.nlm.nih.gov/pubmed/27351882
http://dx.doi.org/10.1007/s00210-016-1270-2

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