Cargando…
C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors
C3 exoenzyme from C. botulinum is an ADP-ribosyltransferase that inactivates selectively RhoA, B, and C by coupling an ADP-ribose moiety. Rho-GTPases are involved in various cellular processes, such as regulation of actin cytoskeleton, cell proliferation, and apoptosis. Previous studies of our group...
Autores principales: | von Elsner, Leonie, Hagemann, Sandra, Just, Ingo, Rohrbeck, Astrid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977334/ https://www.ncbi.nlm.nih.gov/pubmed/27351882 http://dx.doi.org/10.1007/s00210-016-1270-2 |
Ejemplares similares
-
Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation
por: von Elsner, Leonie, et al.
Publicado: (2017) -
Uptake of Clostridium botulinum C3 Exoenzyme into Intact HT22 and J774A.1 Cells
por: Rohrbeck, Astrid, et al.
Publicado: (2015) -
Vimentin Mediates Uptake of C3 Exoenzyme
por: Rohrbeck, Astrid, et al.
Publicado: (2014) -
Cell Entry of C3 Exoenzyme from Clostridium botulinum
por: Rohrbeck, Astrid, et al.
Publicado: (2016) -
The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg–Gly–Asp motif
por: Rohrbeck, Astrid, et al.
Publicado: (2017)