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Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures

The differentiation efficiency of human embryonic stem cells (hESCs) into heart muscle cells (cardiomyocytes) is highly sensitive to culture conditions. To elucidate the regulatory mechanisms involved, we investigated hESCs grown on three distinct culture platforms: feeder-free Matrigel, mouse embry...

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Detalles Bibliográficos
Autores principales: Yeo, Hock Chuan, Ting, Sherwin, Brena, Romulo Martin, Koh, Geoffrey, Chen, Allen, Toh, Siew Qi, Lim, Yu Ming, Oh, Steve Kah Weng, Lee, Dong-Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977469/
https://www.ncbi.nlm.nih.gov/pubmed/27501774
http://dx.doi.org/10.1038/srep31068