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Identifying the topology of signaling networks from partial RNAi data

BACKGROUND: Methods for inferring signaling networks using single gene knockdown RNAi experiments and reference networks have been proposed in recent years. These methods assume that RNAi information is available for all the genes in the signal transduction pathway, i.e., complete. This assumption d...

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Detalles Bibliográficos
Autores principales: Ren, Yuanfang, Wang, Qiyao, Hasan, Md Mahmudul, Ay, Ahmet, Kahveci, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977480/
https://www.ncbi.nlm.nih.gov/pubmed/27490106
http://dx.doi.org/10.1186/s12918-016-0301-4