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The mRNA capping enzyme of Saccharomyces cerevisiae has dual specificity to interact with CTD of RNA Polymerase II
RNA Polymerase II (RNAPII) uniquely possesses an extended carboxy terminal domain (CTD) on its largest subunit, Rpb1, comprising a repetitive Tyr(1)Ser(2)Pro(3)Thr(4) Ser(5)Pro(6)Ser(7) motif with potential phosphorylation sites. The phosphorylation of the CTD serves as a signal for the binding of v...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977518/ https://www.ncbi.nlm.nih.gov/pubmed/27503426 http://dx.doi.org/10.1038/srep31294 |