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Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation
Mast cells play an essential role in initiating allergic diseases. The activation of mast cells are controlled by a complicated signal network of reversible phosphorylation, and finding the key regulators involved in this network has been the focus of the pharmaceutical industry. In this work, we us...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977535/ https://www.ncbi.nlm.nih.gov/pubmed/27502076 http://dx.doi.org/10.1038/srep31320 |