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Biosynthesis and Functional Significance of Peripheral Node Addressin in Cancer-Associated TLO

Peripheral node addressin (PNAd) marks high endothelial venules (HEV), which are crucial for the recruitment of lymphocytes into lymphoid organs in non-mucosal tissue sites. PNAd is a sulfated and fucosylated glycoprotein recognized by the prototypic monoclonal antibody, MECA-79. PNAd is the ligand...

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Detalles Bibliográficos
Autores principales: Weinstein, Aliyah M., Storkus, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977569/
https://www.ncbi.nlm.nih.gov/pubmed/27555845
http://dx.doi.org/10.3389/fimmu.2016.00301