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Superoxide overproduction and kidney fibrosis: a new animal model
OBJECTIVE: To establish whether the mutation in the Immp2L gene induces renal fibrosis and whether aging exacerbates renal morphology in mice. METHODS: Female mutant mice with mutation in the inner mitochondrial membrane peptidase 2-like protein at 3 and 18 months of age were used. Renal fibrosis wa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Ensino e Pesquisa Albert Einstein
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977594/ https://www.ncbi.nlm.nih.gov/pubmed/25993073 http://dx.doi.org/10.1590/S1679-45082015AO3179 |