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Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis

BACKGROUND: We have previously shown that the grape bioactive compound resveratrol (RSV) potentiates grape seed extract (GSE)-induced colon cancer cell apoptosis at physiologically relevant concentrations. However, RSV-GSE combination efficacy against colon cancer stem cells (CSCs), which play a key...

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Detalles Bibliográficos
Autores principales: Reddivari, Lavanya, Charepalli, Venkata, Radhakrishnan, Sridhar, Vadde, Ramakrishna, Elias, Ryan J., Lambert, Joshua D., Vanamala, Jairam K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977641/
https://www.ncbi.nlm.nih.gov/pubmed/27506388
http://dx.doi.org/10.1186/s12906-016-1254-2