Cargando…

Re-emergence of H3N2 strains carrying potential neutralizing mutations at the N-linked glycosylation site at the hemagglutinin head, post the 2009 H1N1 pandemic

BACKGROUND: Seasonally prevalent H1N1 and H3N2 influenza A viruses have evolved by antigenic drift; this evolution has resulted in the acquisition of asparagine (N)-linked glycosylation sites (NGSs) in the globular head of hemagglutinin (HA), thereby affecting the antigenic and receptor-binding prop...

Descripción completa

Detalles Bibliográficos
Autores principales: Ushirogawa, Hiroshi, Naito, Tadasuke, Tokunaga, Hirotoshi, Tanaka, Toshihiro, Nakano, Takashi, Terada, Kihei, Ohuchi, Masanobu, Saito, Mineki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977674/
https://www.ncbi.nlm.nih.gov/pubmed/27503338
http://dx.doi.org/10.1186/s12879-016-1738-1