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Re-emergence of H3N2 strains carrying potential neutralizing mutations at the N-linked glycosylation site at the hemagglutinin head, post the 2009 H1N1 pandemic
BACKGROUND: Seasonally prevalent H1N1 and H3N2 influenza A viruses have evolved by antigenic drift; this evolution has resulted in the acquisition of asparagine (N)-linked glycosylation sites (NGSs) in the globular head of hemagglutinin (HA), thereby affecting the antigenic and receptor-binding prop...
Autores principales: | Ushirogawa, Hiroshi, Naito, Tadasuke, Tokunaga, Hirotoshi, Tanaka, Toshihiro, Nakano, Takashi, Terada, Kihei, Ohuchi, Masanobu, Saito, Mineki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977674/ https://www.ncbi.nlm.nih.gov/pubmed/27503338 http://dx.doi.org/10.1186/s12879-016-1738-1 |
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