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Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage

BACKGROUND: Apicomplexan parasites actively release transmembrane (TM) adhesive proteins involved in host cell attachment and invasion. Rhomboids, a family of intramembrane serine proteases, cleave these secreted adhesive proteins within their TM domains as an essential step in completing the invasi...

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Detalles Bibliográficos
Autores principales: Li, Mingying, Zhang, Xichen, Gong, Pengtao, Li, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977710/
https://www.ncbi.nlm.nih.gov/pubmed/27502595
http://dx.doi.org/10.1186/s13071-016-1728-6