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uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

BACKGROUND: Due to lack of a targeted therapy for the triple-negative breast cancer (TNBC) patients, it is important to explore this aggressive breast cancer type in more detail and to establish novel therapeutic approaches. TNBC is defined negative for the protein expression of oestrogen receptor (...

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Detalles Bibliográficos
Autores principales: Huber, Michaela C., Mall, Rebecca, Braselmann, Herbert, Feuchtinger, Annette, Molatore, Sara, Lindner, Katrin, Walch, Axel, Gross, Eva, Schmitt, Manfred, Falkenberg, Natalie, Aubele, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977758/
https://www.ncbi.nlm.nih.gov/pubmed/27502396
http://dx.doi.org/10.1186/s12885-016-2663-9