Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes

Pathological inclusions containing aggregated, highly phosphorylated (at serine129) α-synuclein (αS pSer129) are characteristic of a group of neurodegenerative diseases termed synucleinopathies. Antibodies to the pSer129 epitope can be highly sensitive in detecting αS inclusions in human tissue and...

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Detalles Bibliográficos
Autores principales: Rutherford, Nicola J., Brooks, Mieu, Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977832/
https://www.ncbi.nlm.nih.gov/pubmed/27503460
http://dx.doi.org/10.1186/s40478-016-0357-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977832/
https://www.ncbi.nlm.nih.gov/pubmed/27503460
http://dx.doi.org/10.1186/s40478-016-0357-9

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