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Cytosolic phospholipase A(2) contributes to innate immune defense against Candida albicans lung infection

BACKGROUND: The lung is exposed to airborne fungal spores, and fungi that colonize the oral cavity such as Candida albicans, but does not develop disease to opportunistic fungal pathogens unless the immune system is compromised. The Group IVA cytosolic phospholipase A(2) (cPLA(2)α) is activated in r...

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Detalles Bibliográficos
Autores principales: Jayaraja, Sabarirajan, Dakhama, Azzeddine, Yun, Bogeon, Ghosh, Moumita, Lee, HeeJung, Redente, Elizabeth F., Uhlson, Charis L., Murphy, Robert C., Leslie, Christina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977843/
https://www.ncbi.nlm.nih.gov/pubmed/27501951
http://dx.doi.org/10.1186/s12865-016-0165-9