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Efficacy and safety of Dexrazoxane (DRZ) in sarcoma patients receiving high cumulative doses of anthracycline therapy – a retrospective study including 32 patients

BACKGROUND: Anthracyclines, as the most effective therapy, are the cornerstone of advanced stage sarcoma treatment. However, anthracyclines can also contribute to myocardial dysfunction and congestive heart failure, ultimately limiting the therapeutic potential of the drug. Coadministration of Dexra...

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Detalles Bibliográficos
Autores principales: Schuler, Markus K., Gerdes, Sebastian, West, Antje, Richter, Stephan, Busemann, Christoph, Hentschel, Leopold, Lenz, Felicitas, Kopp, Hans-Georg, Ehninger, Gerhard, Reichardt, Peter, Pink, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977890/
https://www.ncbi.nlm.nih.gov/pubmed/27507014
http://dx.doi.org/10.1186/s12885-016-2654-x