Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability

Gut commensal bacteria contribute to the pathogenesis of inflammatory bowel disease, in part by activating the inflammasome and inducing secretion of interleukin-1ß (IL-1ß). Although much has been learned about inflammasome activation by bacterial pathogens, little is known about how commensals carr...

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Detalles Bibliográficos
Autores principales: Chen, Kejie, Shanmugam, Nanda Kumar N., Pazos, Michael A., Hurley, Bryan P., Cherayil, Bobby J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978417/
https://www.ncbi.nlm.nih.gov/pubmed/27505062
http://dx.doi.org/10.1371/journal.pone.0160937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978417/
https://www.ncbi.nlm.nih.gov/pubmed/27505062
http://dx.doi.org/10.1371/journal.pone.0160937

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