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IgM-Enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis: A Before-After Cohort Study

INTRODUCTION: Sepsis remains associated with a high mortality rate. Endotoxin has been shown to influence viscoelastic coagulation parameters, thus suggesting a link between endotoxin levels and the altered coagulation phenotype in septic patients. This study evaluated the effects of systemic polysp...

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Detalles Bibliográficos
Autores principales: Wand, Saskia, Klages, Matthias, Kirbach, Christin, Warszawska, Joanna, Meybohm, Patrick, Zacharowski, Kai, Koch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978476/
https://www.ncbi.nlm.nih.gov/pubmed/27504630
http://dx.doi.org/10.1371/journal.pone.0160907