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An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens
The healthy lung maintains a steady state of immune readiness to rapidly respond to injury from invaders. Integrins are important for setting the parameters of this resting state, particularly the epithelial-restricted αVβ6 integrin, which is upregulated during injury. Once expressed, αVβ6 moderates...
Autores principales: | Meliopoulos, Victoria A., Van de Velde, Lee-Ann, Van de Velde, Nicholas C., Karlsson, Erik A., Neale, Geoff, Vogel, Peter, Guy, Cliff, Sharma, Shalini, Duan, Susu, Surman, Sherri L., Jones, Bart G., Johnson, Michael D. L., Bosio, Catharine, Jolly, Lisa, Jenkins, R. Gisli, Hurwitz, Julia L., Rosch, Jason W., Sheppard, Dean, Thomas, Paul G., Murray, Peter J., Schultz-Cherry, Stacey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978498/ https://www.ncbi.nlm.nih.gov/pubmed/27505057 http://dx.doi.org/10.1371/journal.ppat.1005804 |
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