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An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following Influenza A H1N1 infection

Genetic and immunological analysis of host-pathogen interactions can reveal fundamental mechanisms of susceptibility and resistance to infection. Modeling human infectious diseases among inbred mouse strains is a proven approach but is limited by naturally occurring genetic diversity. Using ENU muta...

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Detalles Bibliográficos
Autores principales: Lafferty, Erin I, Flaczyk, Adam, Angers, Isabelle, Homer, Robert, d’Hennezel, Eva, Malo, Danielle, Piccirillo, Ciriaco A, Vidal, Silvia M, Qureshi, Salman T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978536/
https://www.ncbi.nlm.nih.gov/pubmed/24848930
http://dx.doi.org/10.1038/gene.2014.22