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Overexpression of X-Linked Inhibitor of Apoptotic Protein (XIAP) Reduces Age-related Neuronal Degeneration in the Mouse Cochlea

Previously, we showed that age-related hearing loss (AHL) was delayed in C57BL6 mice overexpressing X-Linked Inhibitor of Apoptotic Protein (XIAP), and the delayed AHL was associated with attenuated hair cell (HC) loss in XIAP-overexpressing mice. Similar to other reports, the HC loss in aged mice w...

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Detalles Bibliográficos
Autores principales: Ruan, Qingwei, Zeng, Shan, Liu, Aiguo, Chen, Zhengnong, Yu, Zhuowei, Zhang, Ruxin, He, jingchun, Bance, Manohar, Robertson, George, Yin, Shankai, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978537/
https://www.ncbi.nlm.nih.gov/pubmed/25142138
http://dx.doi.org/10.1038/gt.2014.77