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A Spinal Analogue of Memory Reconsolidation Enables Reversal of Hyperalgesia

Hyperalgesia arising from sensitization of pain relays in the spinal dorsal horn shares many mechanistic and phenotypic parallels with memory formation. We discover that mechanical hyperalgesia can be rendered labile and reversible in mice after reactivation of spinal pain pathways in a process anal...

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Detalles Bibliográficos
Autores principales: Bonin, Robert P., De Koninck, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978538/
https://www.ncbi.nlm.nih.gov/pubmed/24997764
http://dx.doi.org/10.1038/nn.3758