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A Spinal Analogue of Memory Reconsolidation Enables Reversal of Hyperalgesia
Hyperalgesia arising from sensitization of pain relays in the spinal dorsal horn shares many mechanistic and phenotypic parallels with memory formation. We discover that mechanical hyperalgesia can be rendered labile and reversible in mice after reactivation of spinal pain pathways in a process anal...
Autores principales: | Bonin, Robert P., De Koninck, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978538/ https://www.ncbi.nlm.nih.gov/pubmed/24997764 http://dx.doi.org/10.1038/nn.3758 |
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