eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection

Stress granules (SG) are translationally silent sites of RNA triage induced by environmental stresses including viral infection. Here we show that HIV-1 Gag blocks SG assembly irrespective of eIF2α-phosphorylation and even when SG assembly is forced by overexpression of Ras-GAP SH3 domain-binding pr...

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Detalles Bibliográficos
Autores principales: Valiente-Echeverría, Fernando, Melnychuk, Luca, Vyboh, Kishanda, Ajamian, Lara, Gallouzi, Imed Eddine, Bernard, Nicole, Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978539/
https://www.ncbi.nlm.nih.gov/pubmed/25229650
http://dx.doi.org/10.1038/ncomms5819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978539/
https://www.ncbi.nlm.nih.gov/pubmed/25229650
http://dx.doi.org/10.1038/ncomms5819

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