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eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection
Stress granules (SG) are translationally silent sites of RNA triage induced by environmental stresses including viral infection. Here we show that HIV-1 Gag blocks SG assembly irrespective of eIF2α-phosphorylation and even when SG assembly is forced by overexpression of Ras-GAP SH3 domain-binding pr...
Autores principales: | Valiente-Echeverría, Fernando, Melnychuk, Luca, Vyboh, Kishanda, Ajamian, Lara, Gallouzi, Imed Eddine, Bernard, Nicole, Mouland, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978539/ https://www.ncbi.nlm.nih.gov/pubmed/25229650 http://dx.doi.org/10.1038/ncomms5819 |
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