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Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3
The progression of cancers from primary tumors to invasive and metastatic stages accounts for the overwhelming majority of cancer deaths. Understanding the molecular events which promote metastasis is thus critical in the clinic. Translational control is emerging as an important factor in tumorigene...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978545/ https://www.ncbi.nlm.nih.gov/pubmed/24909168 http://dx.doi.org/10.1038/onc.2014.146 |