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Strain-dependent and distinctive T-cell responses to HIV antigens following immunisation of mice with differing chimpanzee adenovirus vaccine vectors

In vivo vaccination studies are conventionally conducted in a single mouse strain with results, only reflecting responses to a single immunogenetic background. We decided to examine the immune response to an HIV transgene (gag, pol and nef fusion protein) in 3 strains of mice (CBA, C57BL/6 and BALB/...

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Detalles Bibliográficos
Autores principales: Herath, S., Le Heron, A., Colloca, S., Patterson, S., Tatoud, R., Weber, J., Dickson, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978701/
https://www.ncbi.nlm.nih.gov/pubmed/27452864
http://dx.doi.org/10.1016/j.vaccine.2016.07.028