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Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins

The exon junction complex (EJC) connects spliced mRNAs to posttranscriptional processes including RNA localization, transport, and regulated degradation. Here, we provide a comprehensive analysis of bona fide EJC binding sites across the transcriptome including all four RNA binding EJC components eI...

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Detalles Bibliográficos
Autores principales: Hauer, Christian, Sieber, Jana, Schwarzl, Thomas, Hollerer, Ina, Curk, Tomaz, Alleaume, Anne-Marie, Hentze, Matthias W., Kulozik, Andreas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978704/
https://www.ncbi.nlm.nih.gov/pubmed/27475226
http://dx.doi.org/10.1016/j.celrep.2016.06.096