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Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency

Purpose: The effects of carnitine depletion upon exercise performance and skeletal muscle mitochondrial function remain largely unexplored. We therefore investigated the effect of N-trimethyl-hydrazine-3-propionate (THP), a carnitine analog inhibiting carnitine biosynthesis and renal carnitine reabs...

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Detalles Bibliográficos
Autores principales: Bouitbir, Jamal, Haegler, Patrizia, Singh, François, Joerin, Lorenz, Felser, Andrea, Duthaler, Urs, Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978712/
https://www.ncbi.nlm.nih.gov/pubmed/27559315
http://dx.doi.org/10.3389/fphys.2016.00345