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Evaluation of assays for drug efficacy in a three-dimensional model of the lung

BACKGROUND: The focus of the outlined work is the establishment of a three-dimensional lung model for various drug-screening applications. METHODS: The non-small cell lung cancer (NSCLC) cell line Colo699 was cultivated as monolayer (2D) on plates for 5 days or as microtissues (3D) using a hanging-d...

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Detalles Bibliográficos
Autores principales: Huber, Julia M., Amann, Arno, Koeck, Stefan, Lorenz, Edith, Kelm, Jens M., Obexer, Petra, Zwierzina, Heinz, Gamerith, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978763/
https://www.ncbi.nlm.nih.gov/pubmed/27424189
http://dx.doi.org/10.1007/s00432-016-2198-0