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Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons

Brain-derived neurotrophic factor (BDNF) plays an important role in hippocampus-dependent learning and memory. Canonically, this has been ascribed to an enhancing effect on neuronal excitability and synaptic plasticity in the CA1 region. However, it is the pyramidal neurons in the subiculum that for...

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Detalles Bibliográficos
Autores principales: Graves, A. R., Moore, S. J., Spruston, N., Tryba, A. K., Kaczorowski, C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978785/
https://www.ncbi.nlm.nih.gov/pubmed/27146982
http://dx.doi.org/10.1152/jn.00186.2016