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Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model
Defects in axonal transport are seen in motoneuronal diseases, but how that impairment comes about is not well understood. In spinal bulbar muscular atrophy (SBMA), a disorder linked to a CAG/polyglutamine repeat expansion in the androgen receptor (AR) gene, the disease-causing AR disrupts axonal tr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978821/ https://www.ncbi.nlm.nih.gov/pubmed/27517091 http://dx.doi.org/10.1523/ENEURO.0062-16.2016 |