Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model

Defects in axonal transport are seen in motoneuronal diseases, but how that impairment comes about is not well understood. In spinal bulbar muscular atrophy (SBMA), a disorder linked to a CAG/polyglutamine repeat expansion in the androgen receptor (AR) gene, the disease-causing AR disrupts axonal tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Halievski, Katherine, Kemp, Michael Q., Breedlove, S. Marc, Miller, Kyle E., Jordan, Cynthia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978821/
https://www.ncbi.nlm.nih.gov/pubmed/27517091
http://dx.doi.org/10.1523/ENEURO.0062-16.2016

Ejemplares similares

Ejemplares similares