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Detecting Recombination Hotspots from Patterns of Linkage Disequilibrium
With recent advances in DNA sequencing technologies, it has become increasingly easy to use whole-genome sequencing of unrelated individuals to assay patterns of linkage disequilibrium (LD) across the genome. One type of analysis that is commonly performed is to estimate local recombination rates an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978882/ https://www.ncbi.nlm.nih.gov/pubmed/27226166 http://dx.doi.org/10.1534/g3.116.029587 |