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Detecting Recombination Hotspots from Patterns of Linkage Disequilibrium

With recent advances in DNA sequencing technologies, it has become increasingly easy to use whole-genome sequencing of unrelated individuals to assay patterns of linkage disequilibrium (LD) across the genome. One type of analysis that is commonly performed is to estimate local recombination rates an...

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Detalles Bibliográficos
Autores principales: Wall, Jeffrey D., Stevison, Laurie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978882/
https://www.ncbi.nlm.nih.gov/pubmed/27226166
http://dx.doi.org/10.1534/g3.116.029587