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A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans

To identify genes that regulate the dynamics of lipid droplet (LD) size, we have used the genetically tractable model organism Caenorhabditis elegans, whose wild-type LD population displays a steady state of size with an upper limit of 3 μm in diameter. From a saturated forward genetic screen of 6.7...

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Detalles Bibliográficos
Autores principales: Li, Shiwei, Xu, Shibin, Ma, Yanli, Wu, Shuang, Feng, Yu, Cui, Qingpo, Chen, Lifeng, Zhou, Shuang, Kong, Yuanyuan, Zhang, Xiaoyu, Yu, Jialei, Wu, Mengdi, Zhang, Shaobing O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978895/
https://www.ncbi.nlm.nih.gov/pubmed/27261001
http://dx.doi.org/10.1534/g3.116.030866