A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription

The protein product of the Homo sapiens TP53 gene is a transcription factor (p53) that regulates the expression of genes critical for the response to DNA damage and tumor suppression, including genes involved in cell cycle arrest, apoptosis, DNA repair, metabolism, and a number of other tumorigenesi...

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Detalles Bibliográficos
Autores principales: Sammons, Morgan A., Zhu, Jiajun, Berger, Shelley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978920/
https://www.ncbi.nlm.nih.gov/pubmed/27334938
http://dx.doi.org/10.1534/g3.116.031534