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Romulus: robust multi-state identification of transcription factor binding sites from DNase-seq data
Motivation: Computational prediction of transcription factor (TF) binding sites in the genome remains a challenging task. Here, we present Romulus, a novel computational method for identifying individual TF binding sites from genome sequence information and cell-type–specific experimental data, such...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978937/ https://www.ncbi.nlm.nih.gov/pubmed/27153645 http://dx.doi.org/10.1093/bioinformatics/btw209 |