miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF

Silicosis is an incurable occupational disease associated with inflammation, fibroblast proliferation and the accumulation of extracellular matrix in lung tissues. The dysregulation of lncRNAs and miRNAs has been implicated in many complex diseases; however, the current understanding of their roles...

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Detalles Bibliográficos
Autores principales: Wu, Qiuyun, Han, Lei, Yan, Weiwen, Ji, Xiaoming, Han, Ruhui, Yang, Jingjin, Yuan, Jiali, Ni, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978961/
https://www.ncbi.nlm.nih.gov/pubmed/27506999
http://dx.doi.org/10.1038/srep30921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978961/
https://www.ncbi.nlm.nih.gov/pubmed/27506999
http://dx.doi.org/10.1038/srep30921

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