Normal tissue radioprotection by amifostine via Warburg-type effects

The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of amifostine on human basal metabolism, mouse liver metabolism and on normal and tumor hepatic cells were studied. Indirect calorimetric canopy tests showed significant reductions in oxygen consumption...

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Detalles Bibliográficos
Autores principales: Koukourakis, Michael I., Giatromanolaki, Alexandra, Zois, Christos E., Kalamida, Dimitra, Pouliliou, Stamatia, Karagounis, Ilias V., Yeh, Tzu-Lan, Abboud, Martine I., Claridge, Timothy D. W., Schofield, Christopher J., Sivridis, Efthimios, Simopoulos, Costantinos, Tokmakidis, Savvas P., Harris, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978965/
https://www.ncbi.nlm.nih.gov/pubmed/27507219
http://dx.doi.org/10.1038/srep30986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978965/
https://www.ncbi.nlm.nih.gov/pubmed/27507219
http://dx.doi.org/10.1038/srep30986

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