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Normal tissue radioprotection by amifostine via Warburg-type effects
The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of amifostine on human basal metabolism, mouse liver metabolism and on normal and tumor hepatic cells were studied. Indirect calorimetric canopy tests showed significant reductions in oxygen consumption...
Autores principales: | Koukourakis, Michael I., Giatromanolaki, Alexandra, Zois, Christos E., Kalamida, Dimitra, Pouliliou, Stamatia, Karagounis, Ilias V., Yeh, Tzu-Lan, Abboud, Martine I., Claridge, Timothy D. W., Schofield, Christopher J., Sivridis, Efthimios, Simopoulos, Costantinos, Tokmakidis, Savvas P., Harris, Adrian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978965/ https://www.ncbi.nlm.nih.gov/pubmed/27507219 http://dx.doi.org/10.1038/srep30986 |
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